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TF Regulon Engineering:
Reducing N₂O Emissions by Increasing NUE
in Bioenergy Crops
ARPA-E TEOSYNTE Project DE-AR0002025
Reducing Nitrogen Loss.
Improving Crop Efficiency.
Transforming Bioenergy Systems.
The TF Regulon Engineering project is an interdisciplinary effort funded through the ARPA-E TEOSYNTE Program, focused on transforming how plants utilize nitrogen.
Nitrogen fertilizers are essential for modern agriculture but are a major source of Nitrous oxide emissions, a potent greenhouse gas and driver of climate change.
Our approach moves beyond traditional breeding and single-gene engineering. We target transcription factor regulons—coordinated gene networks that control nitrogen uptake, assimilation, and metabolism.
Goal:
Develop bioenergy crops that require less fertilizer while maintaining or increasing yield.